Ucwaningo lwe-Genome-wide association (GWAS) luhlose ukuhlonza okuhlukile kofuzo (i-genotype) ehlotshaniswa nezici ezithile (i-phenotype). Ucwaningo lwe-GWA luphenya izimpawu zofuzo eziwela lonke i-genome yenani elikhulu labantu futhi zibikezela izinhlangano ze-genotype-phenotype ngokuhlaziywa kwezibalo ezingeni labantu. Ukulandelanisa kabusha kwezakhi zofuzo kungathola zonke izinhlobo zofuzo. Ngokuhambisana nedatha ye-phenotypic, i-GWAS ingacutshungulwa ukuze kuhlonzwe ama-SNP ahlobene ne-phenotype, ama-QTL kanye nezakhi zofuzo zamakhandidethi, okusekela ngokuqinile ukuzalaniswa kwezilwane/izitshalo kwesimanje. I-SLAF isu lokulandelanisa i-genome elenziwe lula, elithola izimpawu ezisatshalaliswe ngofuzo olubanzi, i-SNP. Lawa ma-SNP, njengezimpawu zofuzo zamangqamuzana, angacutshungulwa ukuze kwenziwe izifundo zokuhlotshaniswa nezici ezihlosiwe. Kuyisu elingabizi kakhulu ekuhlonzeni izici eziyinkimbinkimbi ezihlobene nokuhlukahluka kofuzo.
I-Bioinformatics
