Ii-isoforms ezintsonkothileyo neziguquguqukayo kwizinto eziphilayo ziindlela ezibalulekileyo zofuzo zokulawula ukubonakaliswa kofuzo kunye nokwahluka kweeprotheyini. Ukuchongwa ngokuchanekileyo kwezakhiwo ze-transcript sisiseko sophononongo olunzulu lweendlela zokulawula i-gene expression. Iqonga lolandelelwano lweNanopore lizise ngempumelelo uphononongo lwe-transcriptomic kumgangatho we-isoform. Eli qonga lokuhlalutya lenzelwe ukuhlalutya idatha ye-RNA-Seq eveliswe kwiqonga leNanopore kwisiseko se-genome yereferensi, efezekisa uhlalutyo olunobulunga kunye nobungakanani kwinqanaba le-gene kunye nenqanaba lokubhaliweyo.
Bioinformatics
