Litaba tse monate! BMKGENE e ntlafalitse BMKMANU S letoto la li-spatial transcriptomics chip le thekenoloji ea ho arola lisele e thusoa ke tlhahlobo e nepahetseng ea clonal evolution ea acral melanoma ke sehlopha sa Li Hang, Zhang Ning le Xue Ruidong ho tsoa Univesithing ea Peking, lipatlisiso li hatisitsoe Kankere Cell (IF=50.3).
Boithuto bona, bo ipapisitse le tatellano ea li-multi-omics ho kenyelletsa exome e felletseng, exome ea tikoloho e mengata, transcriptome e ngata, transcriptome ea sele e le 'ngoe, transcriptome ea sebaka, le CODEX proteomics ea sebaka, e senotse ka mokhoa o hlophisehileng mokhoa oa ho iphetola ha lintho oa pele acral melanoma le ho theha. mefuta ea eona ea limolek'hule. Ka ho sebelisa theknoloji ea likaroloana tsa lisele tsa sebaka sa BMKMANU S1000, bakuli ba 10 ba acral melanoma ba ile ba hlahlojoa, ho tiisa likamano tse tobileng tsa sebaka pakeng tsa APOE +/CD163+ TAM le lisele tsa tumor tsa EMT. Ho feta moo, matšoao a macha a pele a ho hlahloba (liphetoho tsa mokhanni le ho kenya letsoho ho kenya letsoho) le matšoao a morao-rao (APOE le CD163) li ile tsa khetholloa le ho netefatsoa, ho fana ka tlhahisoleseding ea bohlokoa bakeng sa tlhahlobo ea pele le phekolo e nepahetseng ea acral melanoma.
Haeba u batla ho tseba haholoanyane ka boithuto bona, kenasehokelo sena.Bakeng sa tlhaiso-leseling e batsi mabapi le lits'ebeletso tsa rona tsa tatelano le bioinformatics, o ka bua le rona Mona.
Nako ea poso: Jul-17-2024