War farxad leh! BMKGENE waxay soo saartay BMKMANU S taxane transcriptomics chip oo leh tignoolajiyada kala qaybinta unugyada oo ay caawisay falanqaynta saxda ah ee saxda ah ee qaabka kobcinta clonal melanoma ee kooxda Li Hang, Zhang Ning, iyo Xue Ruidong oo ka socda Jaamacadda Peking, cilmi-baarista ayaa lagu daabacay Unugga Kansarka (IF=50.3).
Daraasadda, oo ku salaysan isku xigxiga multi-omics oo ay ku jiraan gebi-exome, microdissected multi-gobolada-dhamaadka- exome, bulk transcriptome, transcriptome hal unug, transcriptome spatial, iyo CODEX spatial proteomics, si habaysan ayaa shaaca ka qaaday qaabka horumarinta clonal ee melanoma hore ee acral iyo la aasaasay noocyadiisa molecular hoosaadka. Iyadoo la adeegsanayo farsamada BMKMANU S1000 spatial transcriptome tignoolajiyada qaybta unugyada, bukaanada 10 acral melanoma ayaa la baaray, taasoo xaqiijinaysa isdhexgalka tooska ah ee u dhexeeya APOE +/CD163+ TAMs iyo unugyada burooyinka EMT. Intaa waxaa dheer, calamadaha hore ee ogaanshaha hore (isbeddelka darawalka iyo ku lug lahaanshaha lifaaqa) iyo calaamadaha saadaasha dambe (APOE iyo CD163) ayaa la aqoonsaday oo la ansaxiyay, iyagoo bixinaya macluumaad muhiim ah oo loogu talagalay ogaanshaha hore iyo daaweynta saxda ah ee melanoma acral.
Haddii aad jeclaan lahayd inaad wax badan ka barato daraasaddan, gallink this.Macluumaad dheeraad ah oo ku saabsan adeegyadayada isku xigxiga iyo bioinformatics, waxaad nagula hadli kartaa halkan.
Waqtiga boostada: Jul-17-2024