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Application of Nanopore full-length transcriptome sequencing in isoform-level AS study
TRANSCRIPTOMICS natureCOMMUNICATIONS Full-length transcript characterization of SF3B1 mutation in chronic lymphocytic leukemia reveals downregulation of retained introns Full-length transcripts| Nanopore sequencing| Alternative isoform an...Read more -
Latest successful cases on Nanopore RNA-Sequencing with Biomarker Technologies
Nanopore-based Full-length Transcriptome Sequencing Nanopore sequencing distinguishes itself from other sequencing platforms, in that the nucleotides are read directly without DNA synthesis and generates long reads at tens of kilobases. This empowers direct re...Read more -
Application of full-length amplicon sequencing in microbial diversity studies
MICROBIAL ECOLOGY Agricultural intensification reduces microbial network complexity and the abundance of keystone taxa in roots Full-length Amplicon Sequencing (IT...Read more -
Investigation of microbiome community and function in immobilized bacteria treated soil by full-length 16S sequencing
MICROBIAL Bacterial compatibility and immobilization with biochar improved tebuconazole degradation, soil microbiome composition and functioning Full-length 16S amplicon sequencing | PacBio HiFi | Alpha diversity | Beta di...Read more -
Performance of nanopore long reads in metagenomic studies
METAGENOMICS Complete, closed bacterial genomes from microbiomes using nanopore sequencing Nanopore Sequencing | Metagenomics | MAGs | Bacterial genome circularization | Gut microbiota ...Read more -
Application of Nanopore long-read resequencing in the fight against disease
HUMAN GENOMICS nature genetics Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease ONT resequencing | Illumina | Whole exome sequencing | CRISPR-Cas9 ONT targeted sequ...Read more -
Application of Nanopore-based re-sequencing in COVID19 genetic variants identification
WHOLE GENOME RESEQUENING Genomics monitoring of SARS-CoV-2 uncovers an Nsp1 deletion variant that modulates type I interferon response Nanopore | Illumina | Whole genome resequencing | metagenomics | RNA-Seq | Sanger Bioma...Read more -
Structure variants in Chinese population and their impact on phenotypes, diseases and population adaptation
WHOLE GENOME RESEQUENCING Structure variants in Chinese population and their impact on phenotypes, diseases and population adaptation Nanopore | PacBio | Whole genome re-sequencing | Structural variation callling In this s...Read more -
Four telomere-to-telomere assembled animal and plant genomes
T2T GENOME ASSEMBLY, GAP FREE GENOME 1st Two Rice Genomes1 Title: Assembly and Validation of Two Gap-free Reference Genomes for Xian/indica Rice Reveals Insights into Plant Centromere Architecture Doi: https://doi.org/10.1101/2020.12.24.424073 Post...Read more -
Genome sequences reveal global dispersal routes and suggest convergent genetic adaptations in seahorse evolution
GENOME EVOLUTION nature COMMUNICATIONS Genome sequences reveal global dispersal routes and suggest convergent genetic adaptations in seahorse evolution PacBio | Illumina | Hi-C | WGS | Genetic Diversity | Demographic History | Gene Flow Th...Read more -
A high-quality genome assembly highlights rye genomic characteristics and agronomically important genes
GENOME EVOLUTION nature genetics A high-quality genome assembly highlights rye genomic characteristics and agronomically important genes PacBio | Illumina | Bionano Optical Map | Hi-C Genome Assembly | Genetic Map | Selective Sweeps | RNA...Read more -
Chromosome-scale assembly and analysis of biomass crop Miscanthus lutarioriparius genome
GENOME Chromosome-scale assembly and analysis of biomass crop Miscanthus lutarioriparius genome Nanopore sequencing | Illumina | Hi-C | RNA-sequencing | Phylogeny In this study, Biomarker Techno...Read more -
The genome of Nautilus pompilius illuminates eye evolution and biomineralization
GENOME EVOLUTION The genome of Nautilus pompilius illuminates eye evolution and biomineralization PacBio sequencing | Illumina | Phylogenetic analysis | RNA sequencing | SEM | Proteomics ...Read more
