Evolushọn Genome, Pangenomeme
Gịnị bụ Par-Genome?
Ihe ngosi chikoputara gosiputa na uzo di iche n'etiti umu anumanu nwere ike buru ibu. Otu otu mkpụrụ edemede dị anya iji nweta nkọwapụta nke mkpụrụ ndụ ihe nketa nke otu ụdị. Ebumnuche nke ihe omumu ihe omumu bu inweta eserese nke umu anumanu na akwukwo ihe omuma nke nkpuru obi di iche iche nke otutu di iche iche, nke na - enye ohere nnabata nke di iche.
Ihe omumu nke Pan-Geptome
Ọgụgụ 1 Thekpụrụ nke akwụkwọ nyocha nke PANME bipụtara.
Mara: Onu ogugu na egosiputa ihe eji eme ihe "Pan-genome" dị ka isi okwu iji chọọ aha isiokwu ndị bipụtara na okike, sel na akwụkwọ akụkọ sayensị
a. Na-agụ site na ọtụtụ nlele na-ahazi na ndị na-ese okwu na enweghị nkwekọrịta na-ezukọ ka ọ bụrụ na Nkoko edekọ. Site na ịgbakwunye eriri akwụkwọ akụkọ a na usoro e zoro aka na usoro e zoro aka na usoro e zoro aka na mbụ, a ga-eji ntụnye aka rụrụ arụ. A na-ekpebi mpaghara a na-ekwupụtaghị na mpaghara niile na-agụghachi ndị Pangenome.
b. De Sevembly Mgbakọ nke ihe ọmụmụ nke ọtụtụ ọtụtụ na-enye ụzọ niile n'usoro ọmụmụ ihe iji mata mpaghara ndị a na-ekwupụta.
c. Enwere ike ịrụpụta eserese pan-Genome site na usoro ọmụmụ zuru oke ma ọ bụ site na de Novo Assembly, nke na-echekwa ozi dị iche iche nke mpaghara na-enweghị atụ site na eserese ahụ.
Etu esi arụ PAN-Genome?
Ọgụgụ 2 ntụle nke nsoro pan-na-abịanụ1
a. Na-agụ site na ọtụtụ nlele na-ahazi na ndị na-ese okwu na enweghị nkwekọrịta na-ezukọ ka ọ bụrụ na Nkoko edekọ. Site na ịgbakwunye eriri akwụkwọ akụkọ a na usoro e zoro aka na usoro e zoro aka na usoro e zoro aka na mbụ, a ga-eji ntụnye aka rụrụ arụ. A na-ekpebi mpaghara a na-ekwupụtaghị na mpaghara niile na-agụghachi ndị Pangenome.
b. De Sevembly Mgbakọ nke ihe ọmụmụ nke ọtụtụ ọtụtụ na-enye ụzọ niile n'usoro ọmụmụ ihe iji mata mpaghara ndị a na-ekwupụta.
c. Enwere ike ịrụpụta eserese pan-Genome site na usoro ọmụmụ zuru oke ma ọ bụ site na de Novo Assembly, nke na-echekwa ozi dị iche iche nke mpaghara na-enweghị atụ site na eserese ahụ.
Ebiputara PAN-PAN-PANNOS
Pan Pan-Pen2
Pan tomato-Genimes 3
● Osisi osikapa4
Sunflower Pan-Genome5.
● Soybean pan-Genome 6
Tip pan-keyme7
● Barley Pan-GenomeM
● Ogwe ọkaNke irio
Corghum Pan-Genome10
● phytoplankton panime11
Nrutuaka
1. Bayy Pe, Gọlọ Ọrụ, Scheben A, Batley J, Edward D. Par-Genomes bụ akwụkwọ ọhụụ. Nat osisi. 2020; 6 (8): 914-920. DI: 10.1038 / S41477-020-0733-0
2. Song JM, Guan Z, HU J, et al. Nnukwu mkpụrụ ndụ asatọ dị elu na-ekpughe ihe owuwu Pan-Pan Pan Pan Pan Pan Pan Pan Pan na Brasica napịpịpị. Nat osisi. 2020; 6 (1): 34-45. DI: 10.1038 / S41477-019-0577-7-7-7
3. Gaoo l, Gonca m, Sun H, Et al. Tomato pan na mkpụrụ ndụ mkpụrụ ndụ ọhụrụ na-enweghị atụ na-edozi ekpopụta mkpụrụ. Nati abụba. 2019; 51 (6): 1044-1051. DI: 10.1038 / S41588-019-0410-2
4. zhao q, feng q, lu h, et al. Nyochaa nyocha mkpụrụ ndụ mkpụrụ osisi PAN na-akọwapụta ogo nke mkpụrụ osisi na-akọ na kọfị na osikapa ọhịa [anụ ahụ [bipụta bipụtara na-egosi na okike nke aka. 2018 Ọgọst; 50 (8): 1196]. Nati abụba. 2018; 50 (2): 278-284. DI: 10.1038 / S41588-018-0041-z
5. Hübner S, Bercevich N, ToDco m, et al. Sunflower Pan-mkpụrụ edemede na-egosi na ngwakọ gbanwere ọdịnaya na ọrịa na-eguzogide. Nat osisi. 2019; 5 (1): 54-62. DI: 10.1038 / S41477-018-0329-0
6. Liu y, du h, li p, et al. Pan-keyname nke ọhịa ma zụlite soybean. Sel. 2020; 182 (1): 162-176.e13. DI: 10.1016 / J.Cell.2020.05.023
7. Qin p, lu h, du h, et al. Nyochaa Pan-Mkpụrụ osisi na-ekpughe ngwakọta dị iche iche na-ekpughe ụdị mkpụrụ ndụ zoro ezo [edepụtara na ntanetị dị na mbipụta, 2021 Mee 25]. Sel. 2021; s0092-8674 (21) 00581-x. DI: 10.1016 / j.Cell.2021.04.046
8. Jayakodi m, Padmarasu s, haberrer g, et al. The Barley Pan-Genome na-ekpughe ihe ndị zoro ezo nke ịmụ ọgwụ. Uwa. 2020; 588 (7837): 284-289. DI: 10.1038 / S41586-020-2947-8
9. Sallowhiak s, gar l, monat c, et al. Ọtụtụ mkpụrụ ndụ ọka wit na-ekpughere ọdịiche zuru ụwa ọnụ na oge ọgbara ọhụrụ. Uwa. 2020; 588 (7837): 277-283. DI: 10.1038 / S41586-020-2961-x
10. TAO y, LOO H, XU J, Et al. Udiri vaịn nke dị iche iche n'ime pan-Genome nke akọ na ọnya ọhịa [nke edepụtara na ntanetị, 2021 Mee 20]. Nat osisi. 2021; 10.1038 / S41477-021-021-0925-x. DI: 10.1038 / S41477-021-00925-x
11. fan x, Qiiu H, Han W, Et al. Phytoplankton Pangenome na-ekpughe ọtụtụ profalites prodontiala nke ọrụ mkpụrụ ndụ dị iche iche. Sci dọrọ. 2020; 6 (18): Eaba0111. Bipụtara 2020 Apr 29. DI: 10.11126 / sciadv.Aba0111
Oge Post: Jan-04-2022