Eukaryotic mRNA Analysis (Reference based and de novo options available)
Cov kav dej no siv NGS RNA-Seq cov ntaub ntawv los ntawm kev nkag mus thiab tsim cov txiaj ntsig los ntawm ntau qhov kev soj ntsuam hauv qab no suav nrog tab sis tsis txwv rau: kev ntsuas cov ntaub ntawv zoo,de novtranscription site annotation, sib txawv splicing tsom xam, sib txawv qhia kev tsom xam, muaj nuj nqi annotation thiab enrichment tsom xam.
Ntev tsis-coding RNA Analysis
Ntev tsis-coding RNAs (lncRNA) yog cov ntawv tsis-coding nrog qhov ntev ntev dua 200 nt thiab paub ua lub luag haujlwm hauv chromatin lub koom haum thiab kev tswj hwm. Cov thev naus laus zis dhau los ua ntu zus thiab bioinformatic tau txhawb nqa peb cov kev nkag siab lncRNA cov kab ke thiab cov ntaub ntawv qhia txog kev txheeb xyuas lncRNAs nrog cov haujlwm tseem ceeb ntawm kev tswj hwm. Cov raj xa dej no muab kev tshuaj xyuas lncRNA ntxiv rau cov kev tshuaj ntsuam tau hais hauv Eukaryotic mRNA Analysis pipeline.
16S/18S/ITS amplicon sequencing
Amplicon Sequencing microbial diversity analysis pipeline yog tsim los ntawm ntau xyoo ntawm kev paub hauv microbial diversity project tsom xam. Lub raj xa dej muaj cov qauv kev tshuaj ntsuam xyuas, uas suav nrog cov ntsiab lus tseem ceeb ntawm kev tshawb fawb microbial tam sim no thiab kev tsom xam tus kheej. Daim ntawv tshaj tawm kev tshuaj xyuas yog nplua nuj thiab kev qhia dav, nrog rau kev xaiv los ua ntau hom kev txheeb xyuas tus kheej. Tsis tas li ntawd, cov qauv thiab pab pawg tuaj yeem hloov kho ntawm ya mus rau kev hloov kho ntxiv thiab kev tswj hwm.
Shotgun Metagenomics Analysis
Shotgun Metagenomic Analysis pipeline siv NGS cov ntaub ntawv los ntawm cov khoom sib xyaw genomic muab rho tawm los ntawm ib puag ncig cov qauv. Cov kev txheeb xyuas suav nrog muab cov ncauj lus qhia ntxaws txog hom kev sib txawv thiab kev nplua nuj, cov qauv pej xeem, kev sib raug zoo ntawm phylogenetic, cov noob ua haujlwm, thiab kev sib raug zoo nrog ib puag ncig.
NGS-WGS Variant Analysis
NGS-WGS Variant Analysis yog ib qho kev sib xyaw ua ke nrhiav kom pom cov kav dej uas ua cov ntaub ntawv tswj tau zoo, kev sib txuas ua ke, annotation, thiab kev txheeb xyuas cov noob hloov. Lub raj xa dej ua raws GATK cov kev coj ua zoo tshaj plaws rau SNP thiab InDel tshawb pom thiab siv Manta rau kev hu xov tooj sib txawv.
Genome Wide Association Study (GWAS)
GWAS cov raj xa dej yog qhov kev soj ntsuam qis qis uas siv cov ntaub ntawv VCF yav dhau los thiab cov ntaub ntawv phenotype sib raug rau cov neeg koom nrog cov tswv yim. Siv cov txheej txheem txheeb cais tshwj xeeb, GWAS lub hom phiaj los nthuav tawm cov kev hloov pauv ntawm genome-wide nucleotide sib cuam tshuam nrog qhov sib txawv phenotypic. Nws ua lub luag haujlwm tseem ceeb hauv kev tshawb nrhiav cov noob ua haujlwm cuam tshuam nrog tib neeg cov kab mob nyuaj thiab cov yam ntxwv zoo sib xws hauv cov nroj tsuag thiab tsiaj txhu.
Bulk Segregation Analysis (BSA)
Kev tshuaj xyuas BSA suav nrog kev sib koom ua ke ntawm cov tib neeg uas muaj qhov zoo tshaj plaws phenotypic los ntawm cov neeg sib cais. Los ntawm kev sib piv qhov sib txawv ntawm qhov sib txawv ntawm cov qauv sib xyaw, txoj hauv kev no tau txheeb xyuas qhov sib txuas ntawm cov cim molecular uas cuam tshuam nrog cov hom phiaj. Dav siv nyob rau hauv genetic mapping ntawm cov nroj tsuag thiab tsiaj txhu, nws yog ib qho tseem ceeb cuab tam rau marker-pab yug me nyuam.
Evolutionary Genetics Analysis
Lub Evolutionary Genetics Analysis workflows leverages BMKGENE qhov kev paub dhau los hauv cov haujlwm genetic evolution tej yaam num thiab suav nrog phylogenetic ntoo tsim, linkage disequilibrium tsom xam, genetic ntau haiv neeg ntsuam xyuas, xaiv cheb qhia, kinship tsom xam, lub ntsiab tivthaiv tsom xam, thiab pej xeem tus qauv characterization.
