Hoʻohālikelike GENOMICS
Loaʻa nā lawelawe lawelawe
●Nā hōʻike loea a me nā moʻolelo paʻi: me ka hōʻiliʻiliʻia, ua hoʻopauʻo BMKGENE ma luna o 90 mau hana hoʻohālikelike genomictive, me kahi mea hoʻopiʻi maikaʻi i hiki i 900.
●Ke nānā aku neiʻo Biinformation Bihiin Hanohano:ʻO ka helu helu helu helu i nā mea e like me kaʻewalu mau loa e pono ai, e hāʻawi ana i nā kiʻi kiʻekiʻe a me nā kiʻi i hoʻolālāʻia a me nā mea i kohoʻia no ka weheweheʻana i nā hopena
●ʻO ka hui pūʻanaʻo Biinformatics Biinformatics a me ka pōkole pōkole pōkole: me kaʻike nui ma ka hoʻohālikelike genomicsive genomics
●Kākoʻo kākoʻo:Hoʻopili kā mākou kūpaʻaʻana ma mua o ka hoʻopauʻana i kahi papa hana me kahi manawa lawelawe 3-mahina ma hope o ka lawelawe lawelawe. I kēia manawa, hāʻawi aku mākou i nā hana hahai, a me nā manaʻo e hoʻopiʻiʻia i kōkua, a me ke kau e pili ana i nā noi.
Nāʻikepili lawelawe
| Kuhiʻia ka manawa-a puni ka manawa | Ka helu o nāʻanoʻano | Hoʻoponopono |
| 30 mau lā hana | 6 - 12 | ʻO ka Clustering Family Clustering ʻO ka hoʻonuiʻana o kaʻohana General Phyloge AnnageNitic Sig i kūkulu i ʻO ka hana DIvergence Tivergen LRR INVITET manawa (no nā mea kanu) Pau ka hoʻolahaʻana o Genome (no nā mea kanu) Ke kumu koho ʻO ka loiloi syntony |
Nā Piʻiʻo BioinformaticES
●ʻO kaʻohana aloha
● Phylogenetics
●ʻO ka wā make
●
● Kaikalike pili pāʻani
Nā koi koi a me ka laweʻana
Nā Manaʻo Manaʻo:
Tissue or dna no genome sequening a me ka hui
No ka kiko
| Nāʻano | Kahi | Mākaʻikaʻi | Pacbio Ccs |
| Holoholona | ʻO nā kiko Visceral | 0.5 ~ 1 g | ≥ 3.5 g |
| Muscle tissue | |||
| ≥ 5.0 g | |||
| ≥ 5.0 ml | |||
| ʻO ke koko mammania | |||
| ≥ 0.5 ml | |||
| ʻO ke koko wai / iʻa | |||
| Meakanu | Lau hue | 1 ~ 2 g | ≥ 5.0 g |
| Petal / Stoem | 1 ~ 2 g | ≥ 10,0 g | |
| All / hua | 1 ~ 2 g | ≥ 20.0 g | |
| Manu | Cell cell | - | ≥ 1 x 108 |
'Ikeʻike
ʻO nā faile sente sensent
E holo ka lawelawe lawelawe
Hoʻolālā hoʻokolohua
Nā Hoʻounaʻana
Hana ka waihona puke
Hoahewa ana
Nāʻikepiliʻikepili
Ma hope o nā lawelawe kūʻai
*ʻO nā hopena demo i hōʻikeʻia ma aneʻi mai nā mea āpau mai Genomes i paʻiʻia me nāʻenehana biorker
1.LLTR E hoʻokomo i ka manawa helu: hōʻikeʻia ke kiʻi i kahi'āpana bimdal kūʻokoʻa ma LRT-LRY e pili ana i ka MYSE GYE TYY. ʻO ka pīkoi hou loa a puniʻo 0.5 miliona mau makahiki i hala.
Licang et al.,Nā akua kūlohelohe, 2021
2.phylogeny a me keʻano o ka hanaʻohana ma Chayote (Sechium Edule) Ua loaʻa iā Chayote mai ka Groke Gound ma kahi o 27-45 mya a me My ROTOME FUPlication (WGD) i keʻano he cucilicatacee.
Fu A et al.,Hōʻike Huakaʻi Hōʻailona, 2021
ʻO 3.SysYntyyy:ʻO kekahi mauʻano e pili ana i nā gines e pili ana i nā phytormmodes i loaʻa i ka nui o ke kūkuluʻana i ka couyte ʻOi aku ma waena o Chayote a me Squash iʻoi aku ka kiʻekiʻe ma mua o ka ma waena o ka chayote a me nā snake gourd.
Fu A et al.,Hōʻike Huakaʻi Hōʻailona, 2021
4.Geneʻohanaʻohana: Ke hōʻike neiʻo Kegg Intrichment ma ka hoʻonuiʻana i kaʻohana Gontensis a me G.DurSothesi a G.
Yang Z et al.,ʻO BMC Biology, 2021
5.We i ka hōʻikeʻana o Genokeation i ka hōʻikeʻana: 4DTVV a me Ks ka helu helu helu i hōʻikeʻia i ka hananaʻo Genome Duplication. Nā peks o nā intraspeies hōʻike i nā hananaʻelua. Nā peaks o nā interspeces hōʻikeʻia i hōʻikeʻia i nā hanana. Ua hōʻike kaʻike i ka hoʻohālikelikeʻana me nāʻano e pili ana i nā mea e pili ana i nā mea hou aʻe,ʻo Europaaaa i hele hou ma kahi nui o ka nui.
Rao g et al.,Hōʻike Huakaʻi Hōʻailona, 2021
Hihia bmk
Rose me kaʻole o nā kumukūʻai: nā mea nānā genomic i hoʻopiliʻia e pili ana i ka hoʻopiliʻana
Paʻiʻia: Hōʻike Kānāwai Kāleʻa Kākoʻo, 2021
ʻO ka hoʻolālāʻana o ka hana:
'Basye'sHaaheo'(R.Wichinan) Genome:
Kokoke. 93 x pacbio + apple. 90 x nanopore + 267 x illmiina
Nā hopena Kūlana
1. Ua kūkuluʻiaʻo R.wicuraina R.wicuraana genome i ka hoʻohanaʻana i nā hana lōʻihi ʻO ka Susco koho i kohoʻia he 93.9%. Ka hoʻohālikelikeʻana me ka "blush kahiko" (Haploob) R.Wicerana Genome he 32,674 Nā Kūlana Kūʻai Kūʻai Kūʻai Kūʻai.
2.Multi-omitic hui i ka loiloiʻana, nona nā mea hoʻohālikelike, transtcriptsomics, e hōʻike i ka heluna Genetic Eia kekahi,ʻanoʻanoʻano o nā genes pili i ka qtl e pili ana i ka hoʻopiliʻana i ka papa.
Hoʻohālikelike Hoʻohui Hoʻohui ma waena o Basye ʻO ka hoʻonuiʻana o ka mea kūʻokoʻa ma NaC a me Far1 / FRS Gutyʻohana nui loa e pili ana i ka piliʻana me ke kū'ēʻana i kahi wahiʻeleʻele.
Hoʻohālikelike i nā loiloi genmics ma waena o bt a me haploob genmes.
Zhong, M., et al. "Rose me kaʻole o nā mea kūʻai aku: nā mea nānā genomic i hoʻopiliʻia e pili ana i ka hoʻopiliʻana"Hōʻike Kānāwai Kāleʻa Kākoʻo, 2021 ;, nwab0992.
