Labarai masu kayatarwa! BMKGENE ya haɓaka guntuwar ƙirar sararin samaniya ta BMKMANU S tare da fasahar rarraba tantanin halitta wanda aka taimaka ta hanyar bincike mai zurfi na tsarin juyin halitta na acral melanoma na ƙungiyar Li Hang, Zhang Ning, da Xue Ruidong na Jami'ar Peking, an buga binciken a cikin Ciwon daji (IF=50.3).
Binciken, dangane da jerin abubuwan omics da suka haɗa da cikakken-exome, microdissected Multi-regional whole-exome, bulk transcriptome, transcriptome guda-cell, bayanan sararin samaniya, da CODEX sararin samaniya proteomics, ya bayyana tsarin juyin halittar clonal na farkon acral melanoma da kafa. subtypes ta kwayoyin halitta. Ta hanyar yin amfani da fasahar ɓoyayyiyar ɓangarori na BMKMANU S1000 na sararin samaniya, an bincika marasa lafiya na acral melanoma 10, suna tabbatar da hulɗar sararin samaniya tsakanin APOE +/ CD163+ TAMs da ƙwayoyin tumor EMT. Bugu da ƙari kuma, an gano sabbin alamomin bincike na farko (maye gurbin direba da shigar da ƙari) da kuma alamun ƙididdiga na ƙarshe (APOE da CD163) kuma an tabbatar da su, suna ba da mahimman bayanai don ganewar asali da kuma daidaitaccen magani na acral melanoma.
Idan kuna son ƙarin koyo game da wannan binciken, shigawannan mahada.Don ƙarin bayani kan jerin abubuwan mu da sabis na bioinformatics, zaku iya magana da mu anan.
Lokacin aikawa: Yuli-17-2024