-
BMKGENE Experience of WGBS&RNA-seq Joint Analysis
DNA methylation is one of the most extensively studied epigenetic modifications. It plays a crucial role in genome stability, gene transcription regulation, and trait development. The transcription of genes is determined by their methylation status, with low methylation levels associated with ge...Read more -
Featured Publication—Microbiome-metabolome analysis directed isolation of rhizobacteria capable of enhancing salt tolerance of Sea Rice 86
The article titled “Microbiome-metabolome analysis directed isolation of rhizobacteria capable of enhancing salt tolerance of Sea Rice 86” published in Science of the Total Environment explores the rhizosphere bacterial diversity and soil metabolome of SR86 seedlings under varying sa...Read more -
Featured Publication—Obese Ningxiang pig-derived microbiota rewires carnitine metabolism to promote muscle fatty acid deposition in lean DLY pigs
BMKGENE provided full-length 16s amplicon sequencing and metagenomics sequencing services for the article “Obese Ningxiang pig-derived microbiota rewires carnitine metabolism to promote muscle fatty acid deposition in lean DLY pigs”, which was published in The Innovation. This study aimed to unv...Read more -
Featured Publication—Mining Genes Related to Fruit Quality in Sweet Oranges Based on Specific Locus Amplified Fragment Sequencing
One important horticultural characteristic that distinguishes navel oranges from other common sweet orange varieties is the presence of a navel on the fruit. This feature is also an important criterion for the classification of sweet orange horticultural varieties. BMKGENE’s clients utiliz...Read more -
Featured Publication—Capturing the microbial dark matter in desert soils using culturomics-based metagenomics and high-resolution analysis
BMKGENE provided full-length 16s amplicon sequencing and metagenomics sequencing services for this study “Capturing the microbial dark matter in desert soils using culturomics-based metagenomics and high-resolution analysis”, which was published in npj Biofilms and Microbiomes. This study intro...Read more -
Featured Publication—The attenuating effects of synbiotic containing Cetobacterium somerae and Astragalus polysaccharide against trichlorfon-induced hepatotoxicity in crucian carp (Carassius carass...
BMKGENE provided 16s amplicon sequencing services for this study: The attenuating effects of synbiotic containing Cetobacterium somerae and Astragalus polysaccharide against trichlorfon-induced hepatotoxicity in crucian carp (Carassius carassius), which was published in Journal of Hazardous Mate...Read more -
Featured Publication—Genetic Diversity and Population Structure in Solanum nigrum Based on Single-Nucleotide Polymorphism (SNP) Markers
For large-scale populations, we recommend using specific-locus amplified fragment sequencing (SLAF) for genome sequencing and variant detection, enabling the analysis of evolutionary relationships among different subgroups. This article serves as a valuable case study using our approach. The ana...Read more -
Featured Publication—3D disorganization and rearrangement of genome provide insights into pathogenesis of non-alcoholic fatty liver disease (NAFLD) by integrated Hi-C, Nanopore, and RNA sequencing
BMKGENE provided Hi-C sequencing services for this study: 3D disorganization and rearrangement of genome provide insights into pathogenesis of non-alcoholic fatty liver disease (NAFLD) by integrated Hi-C, Nanopore, and RNA sequencing, which was published in Acta Pharmaceutica Sinica B. In this s...Read more -
Featured Publication—Full-length transcriptome sequencing of lymphocytes respond to IFN-γ reveals a Th1-skewed immune response in flounder (Paralichthys olivaceus)
BMKGENE provided full-length transcriptome sequencing services for this study : Full-length transcriptome sequencing of lymphocytes respond to IFN-γ reveals a Th1-skewed immune response in flounder (Paralichthys olivaceus), which was published in Fish & shellfish immunology. In this study, f...Read more -
Featured Publication—Saltwater intrusion affecting NO2− accumulation in demersal fishery species by bacterially mediated N-cycling
BMKGENE provided 16s amplicon and metagenomic sequencing services for this study： Saltwater intrusion affecting NO2− accumulation in demersal fishery species by bacterially mediated N-cycling, which was published in Science of The Total Environment. This study investigates the underlying effect...Read more -
Featured Publication—STEEL enables high-resolution delineation of spatiotemporal transcriptomic data
BMKGENE provided spatial transcriptome sequencing services for the study “STEEL enables high-resolution delineation of spatiotemporal transcriptomic data”, which was published in Briefings in Bioinformatics. This study proposed an unsupervised and manifold learning-based algorithm, ...Read more -
Featured Publication—Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma
BMKGENE provided ONT long-read nanopore RNA sequencing and ATAC-seq service for the study “Epigenetic and transcriptional activation of the secretory kinase FAM20C as an oncogene in glioma”, which was published in the 《Journal of Genetics and Genomics》. This study construct...Read more -
Featured Publication—A cascade nanoreactor for enhancing sonodynamic therapy on colorectal cancer via synergistic ROS augment and autophagy blockage
BMKGENE provided transcriptome sequencing service for the study “A cascade nanoreactor for enhancing sonodynamic therapy on colorectal cancer via synergistic ROS augment and autophagy blockage“, which was published in Nano Today.This study aims to improve the antitumor efficiency of ...Read more
